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Evidence-ranked supplement database

Find supplements worth taking.

Compare evidence, dosage, safety, interactions and real-world usefulness across supplements, goals and stacks.

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226 ranked supplements

Heart/Inflammation/Mood

Omega-3

$$
Score100
evidenceA
Safe
Lowers triglyceridesModestly lowers blood pressureModestly lowers CV event risk
Performance/Cognition/Mobility

Creatine

$
Score100
evidenceA
Safe
Improves strength and powerIncreases lean mass with trainingImproves function in older adults
Deficiency/Longevity/Immunity

Vitamin D

$
Score95
evidenceA
Caution
Corrects vitamin D deficiencySupports bone healthReduces respiratory infection risk
Deficiency/Heart/Sleep

Magnesium

$
Score92
evidenceA
Caution
Corrects magnesium deficiencyLowers blood pressure modestlyImproves sleep quality
Cognition/Performance/Weight

Caffeine

$
Score92
evidenceA
Caution
Reduces fatigue and sleepinessBoosts exercise performanceImproves reaction time, attention
Deficiency/Women/Cognition

Iron

$
Score85
evidenceA
Caution
Corrects iron-deficiency anemiaPrevents maternal anemiaReduces fatigue when iron is low
Performance/Weight/Longevity

Protein

$$
Score85
evidenceA
Safe
Enhances strength with trainingSupports lean mass preservationReduces sarcopenia in older adults
Sleep/Mood/Heart

Melatonin

$
Score80
evidenceA
Safe
Reduces sleep onset latencyMay reduce preoperative anxietyMay lower nocturnal blood pressure
Digestion/Heart/Weight

Psyllium husk

$
Score75
evidenceA
Safe
Improves bowel regularityLowers LDL cholesterolImproves glycemic control
Deficiency/Immunity/Heart

Vitamin C

$
Score73
evidenceA
Safe
Corrects deficiency/scurvyShortens common cold durationLowers blood pressure modestly
Deficiency/Longevity/Heart

Vitamin K

$
Score72
evidenceB
Caution
Corrects low vitamin K statusSupports bone densityMay reduce arterial stiffness
Women/Deficiency/Heart

Folic Acid

$
Score72
evidenceA
Caution
Prevents neural tube defectsCorrects folate deficiencyReverses megaloblastic anemia
12 of 226 supplements