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Hormonal

Fadogia agrestis

Botanical extract studied mainly in animals; human evidence for testosterone or libido benefits is lacking.

Fadogia agrestis
8
score
D
evidence
Unsafe
risk

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Significant safety concern

This supplement has a significant safety concern and should be avoided unless medically supervised.

Quick Take

Skip it — claims rest on animal data, and human safety and benefit data are lacking.

Fadogia agrestis is a West African shrub used in traditional medicine; supplements are made from bark or whole-plant extracts, not foods. Animal studies suggest it may affect the hypothalamic-pituitary-gonadal axis and testicular steroid production. Reported effects include possible increases in testosterone, libido, and sperm-related outcomes, but none are confirmed in humans. If anyone uses it, it is mainly for experimental supervised use.

Potential benefits

01
May raise testosterone
02
May improve libido
03
May support sperm parameters

Protocol

Amount
No established dose
Frequency
Not established
When
Not established

Onset Time

Unknown in humans; no clinical trials define onset.

Who Should Consider

No general consumer group at this time

How It Works

In animal studies, Fadogia agrestis appears to influence the hypothalamic-pituitary-gonadal axis and testicular steroidogenesis, which could raise androgen production. Human confirmation is lacking.

Updated 5/19/2026

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