Immunity/Inflammation/Weight

Chaga

Medicinal mushroom marketed for immunity and antioxidants, but human evidence is too limited to support clear benefits.

score

evidence

Caution

risk

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Use with caution

This supplement may interact with medications, medical conditions or sensitive populations. Review safety before use.

Overview

Forms

Safety

Stack

Quick Take

Skip it for now — claims are mostly preclinical, with too little human evidence to justify routine use.

Chaga is a fungus that grows mainly on birch trees and is sold as tea, powder, or extract. It contains polysaccharides, polyphenols, and triterpenes with antioxidant, anti-inflammatory, and immunomodulatory activity in lab studies. The main claims are lower oxidative stress, immune support, reduced inflammation, and possible glucose effects, but human trials are sparse and not conclusive. It is most relevant to people interested in traditional mushroom products.

Potential benefits

May reduce oxidative stress

May modulate immune response

May reduce inflammatory markers

May improve glucose control

Protocol

Amount

500-1000 mg extract

Frequency

Once daily

When

Any time of day — consistency matters more than timing.

Onset Time

Unknown — no well-established human timeline

Who Should Consider

People specifically interested in traditional mushroom use

How It Works

Chaga contains beta-glucan-like polysaccharides, polyphenols, and triterpenes that can alter macrophage and NK-cell signaling and reduce oxidative stress in preclinical models. Those mechanisms may explain the immune and anti-inflammatory claims, but human confirmation is limited.

Updated 5/19/2026